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RESEARCH

The Science of Prediction

DeepInsight uses a novel modeling approach to accurately map cell growth within confined environments, predicting later behaviours from early imaging data alone.

We are actively compiling data on label-free phenotypic clustering to link growth patterns with stability.

Read the published paper →

Model Methodology

Four proprietary neural networks, designed and trained in-house. No third-party foundation models.

The team behind DeepInsight designed and deployed the VIPS single-cell printer and its production AI models — the system now used across hundreds of CLD laboratories worldwide. That same first-hand understanding of cell-line development imaging and machine learning at production scale now drives the DeepInsight pipeline. Every network is designed, trained, and deployed by engineers who have lived the CLD workflow.

01

Cell Localisation

Detects and locates every cell within brightfield well images. Precise cell-level positioning across the full imaging field.

02

Cell Categorisation and Measurement

Classifies cell types and measures morphological features. Builds a quantitative profile for each detected cell.

03

Counting, Summarisation and Growth Profiling

Aggregates per-well and per-colony cell counts. Tracks population growth over time and profiles growth dynamics.

04

Neural Fingerprinting and Clustering

Generates a unique optical fingerprint for every detected cell. Clusters clones by phenotype to surface the most stable, high-performing candidates.

DeepInsight model architecture. A simplified overview of the AI pipeline. Runs on existing brightfield imaging data from any device. Images are processed through four proprietary neural networks, producing predictive growth models, clone rankings, and full lineage traceability. All networks are designed and trained in-house; no third-party foundation models are used.

Key models

Each model addresses a specific decision point in the CLD workflow. Together they build a complete clone-level profile, helping you select the best candidates with confidence.

Growth prediction

Exponential sigmoid growth model splits each clone's trajectory into early passive and later dominant growth components. From the first few days of culture, the model predicts which clones will sustain robust growth through to the end of the workflow.

Read the paper

Label-free cell counting

Cell counts without stains or fluorescent labels. Validated against manual counting and fluorescence methods at production scale. Per-well and per-colony counts feed directly into growth rate calculations.

Clone ranking and fingerprinting

Multi-factor ranking across growth rate, recovery speed, and colony density. The ranking surface flags the highest-potential clones for progression while catching underperformers before they reach the banking stage.

Validation

Trained and validated against production CLD data at scale.

Manual cell counting by experienced CLD scientists
Fluorescence-based viability assays
End-point titre measurements for growth rate validation
Cross-referenced growth profiling and additional instrument endpoints

DeepInsight models have been trained and validated across thousands of production plates — representing hundreds of thousands of wells — from collaboration partners and internal datasets. Validation metrics span cell count accuracy against manual counts by experienced CLD scientists, cross-referenced against fluorescence-based viability assays and end-point titre measurements. Growth profiling has been independently corroborated against additional instrument endpoints. The result is a model suite that performs reliably across diverse instrument stacks, cell lines, and laboratory conditions.

Data and intellectual property

Your data stays yours.

Customer data isolation

Your imaging data is never used to train models for other customers. Only data shared with us through partnerships is used for model training. Your data stays yours.

UK infrastructure

Purpose-built AI compute facility in Dorset, UK. GPU-powered inference on our own processing and storage hardware. GDPR-compliant. No external cloud providers.

Geographic expansion

Additional geographic regions planned, with USA processing capability initially.

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See how these models deliver decision-grade analytics in production.

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